Lama4 gene

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August undefined, 2024

http://www.bioon.com.cn/doc/showarticle.asp?newsid=112118 TīmeklisThe LAMA4 p.Asp1309Asn variant was predicted to be likely pathogenic according to international guidelines. The other two families had no identifiable potentially deleterious variants. Conclusions: Inheritance of two genetic variants may have a synergistic or dose effect to cause severe DCM.

16775 - Gene ResultLama4 laminin, alpha 4 [ (house …

TīmeklisMore than 100 LAMA2 gene mutations have been identified in individuals with LAMA2-related muscular dystrophy, a disorder that causes weakness and wasting (atrophy) … TīmeklisThis gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. potted artificial christmas tree with lights

LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a …

TīmeklisThis gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of … TīmeklisLAMA4 is specifically up-regulated on both mRNA and protein levels in hepatocelluar carcinoma. The strong correlation between high expression … Tīmeklis2010. gada 23. marts · Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide … touchscreen browser for surface

Human Gene LAMA4 (ENST00000230538.12) from GENCODE V43

LAMA4 Gene - Somatic Mutations in Cancer - Wellcome Sanger …

Tīmeklis2007. gada 14. dec. · Since the cDNA of LAMA4 has 6,297 nucleotides (GenBank Accession number: NM_002290), the sequences of oligonucleotide primers for RT-PCR of LAMA4 gene were designed at the 3′ end of the cDNA (Fig. 1 ), the expected amplified DNA is a 427 bp fragment, including the translation terminate site (TGA). … potted artificial flocked christmas treeTīmeklis2024. gada 21. marts · LAMA4 (Laminin Subunit Alpha 4) is a Protein Coding gene. Diseases associated with LAMA4 include Cardiomyopathy, Dilated, 1Jj and Familial Isolated Dilated Cardiomyopathy . Among its related pathways are Integrin Pathway … touch screen browser games

"TīmeklisLAMA4 is specifically up-regulated on both mRNA and protein levels in hepatocelluar carcinoma; potential role in hepatocarcinogenesis and tumor … " - Lama4 gene

Lama4 gene

NM_001105206.3(LAMA4):c.5450T>C (p.Ile1817Thr) AND …

Tīmeklis2024. gada 9. aug. · Genetic alterations and DNA methylation of LAMA4 were analyzed using cBioPortal and MethSurv. LinkedOmics was applied to identify coexpressed genes of LAMA4. The association between LAMA4 and infiltration of immune cells was explored using Tumor Immune Estimation Resource (TIMER) and GEPIA. Tīmeklis2024. gada 8. nov. · LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a Role in IGFBP6-Dependent Effects on Phenotype of Basal-Like Breast Cancer …

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Tīmeklis2024. gada 26. nov. · NM_001105206.3(LAMA4):c.5450T>C (p.Ile1817Thr) AND Cardiomyopathy Clinical significance: Benign (Last evaluated: Nov 26, 2024) Review status: 1 star out of maximum of 4 stars TīmeklisLAMA4 variants in DCM The table below lists the LAMA4 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease.

Tīmeklis2024. gada 8. marts · Mice with a null mutation in the laminin α4 (LAMA4) gene (KO) exhibit resistance to obesity and enhanced expression of thermogenic fat markers in … Tīmeklis2024. gada 6. apr. · Recombinant Laminin Alpha 4 (LAMa4) [ PROPERTIES ] Source: Prokaryotic expression. Host: E. coli Residues: Ile832~Lys1039 Tags: N-terminal His-Tag Tissue Specificity: Lung, Liver, Kidney, Spleen. Subcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane. Purity: >95% Traits: …

Tīmeklis2016. gada 7. janv. · Gene: LAMA4:laminin subunit alpha 4 [Gene - OMIM - HGNC] Variant type: single nucleotide variant Cytogenetic location: 6q21 Genomic location: Chr6: 112120303 (on Assembly GRCh38) Chr6: 112441506 (on Assembly GRCh37) Preferred name: NM_001105206.3(LAMA4):c.4645A>T (p.Asn1549Tyr) Other names: Tīmeklis2013. gada 16. maijs · Screening the LAMA4 gene by SSCP in an additional 200 Japanese CMD patients revealed no variants. Animal Model Thyboll et al. (2002) …

TīmeklisThe LAMA2 gene provides instructions for making a part (subunit) of certain members of a protein family called laminins. Laminin proteins are made of three different subunits called alpha, beta, and gamma. There are several forms of each subunit, and each form is produced from instructions carried by a different gene.

TīmeklisLaminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms … potted artificial fir pine treeTīmeklisIn conclusion, this study identified a severe case of DCM with digenic inheritance of two variants in MYH7 and LAMA4 detected by a 181-gene NGS panel. These results … touchscreen bss blu1TīmeklisEnabling this option will make it much easier to find gene-specific primers since there is no need to distinguish between splice variants. This option requires you to enter a refseq mRNA accession or gi or fasta sequence as PCR template input because other type of input may not allow the program to properly interpret the result. potted artificial flowers reading paTīmeklisTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. LAMA4. potted artificial flowers for cemeteryTīmeklisLama4 Name laminin, alpha 4 Synonyms laminin [a]4 Feature Type protein coding gene IDs MGI:109321 NCBI Gene: 16775 Alliance gene page Transcription Start Sites 7 … touch screen bticinoTīmeklisENST00000519245.1. LAMA4-020. 587. No protein. An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the … touchscreen bubbles on dellTīmeklis2024. gada 17. janv. · Lama4 laminin, alpha 4 [ (house mouse)] Gene ID: 16775, updated on 8-Nov-2024 Summary Predicted to enable signaling receptor binding activity. Predicted to be an extracellular matrix structural constituent. Involved in negative regulation of cold-induced thermogenesis. touchscreen browser games