WebApr 9, 2024 · Anticancer medication doxorubicin was encapsulated in PLGA-PEG-FOL carrier that was designed to target tumors by Zhao et al. Drug release in the endosomes is hastened by the addition of pH-sensitive poly b-amino ester (PAE) to PLGA-PEG-FOL to develop mixed micelles. WebApr 14, 2024 · The anticancer effect of PTX/SRF combination therapy was improved compared to the use of a single drug. In the xenografted BALB/c mouse model, the tumor growth inhibition rate of PTX/SRF micelles ...
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WebRedox and pH Dual-Responsive Polypeptide Micelles for Doxorubicin Delivery with Enhanced Anticancer Efficacy Hanlei Xing School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China WebApr 22, 2016 · The instability of PEGylated polylactide micelles is a challenge for drug delivery. Stereocomplex interaction between racemic polylactide chains with different configurations provides an effective strategy to enhance the stability of micelles as the nanocarriers of drugs. In this work, a stereocomplex micelle (SCM) self-assembled from … songs made in the 70s
Biodegradable polymeric nanoparticles based on amphiphilic
WebThe polymer could self-assemble into micelles and solubilize hydrophobic anticancer drugs such as paclitaxel (PTX) in the core. Combining the effect of TPE, mPEG, and disulfide … WebFeb 2, 2024 · The physical incorporation or solubilisation of drugs within block copolymer micelles is generally preferred over micelle-forming polymer-drug conjugates, especially for hydrophobic drug molecules. Indeed, many polymers and drug molecules do not contain reactive functional groups for chemical conjugation, and therefore, specific block … WebSep 15, 2024 · The article presents the design and outcomes of various types of stimuli-responsive polymeric micelles, including their clinical status, and the type of copolymers used, their physicochemical properties and characterization. Polymeric micelles have gained interest as novel drug delivery systems for the treatment and diagnosis of cancer, as they … songs make you feel a force is watching you