WebDec 7, 2015 · Rationale Respiratory syncytial virus (RSV) infection in preterm and newborn infants can result in severe bronchiolitis and hospitalization. The lamb lung has several key features conducive to modeling RSV infection in human infants, including susceptibility to human strains of RSV such as the A2, Long, and Memphis Strain 37 (M37). In this study, … WebMar 18, 2014 · To test the hypothesis that sucrose enhances RSV stability and infectivity, a series of in vitro experiments were conducted with RSV strain Memphis 37 stored at varying concentrations (0%, 3%, 5%, 8%, 10%, 15%, and 20%) of sucrose as a possible cryo- and nebulization protectant.

Respiratory syncytial virus human experimental infection model ... - PubMed

Webvolunteers aged 60–75 years and 21 aged 18–55 years were inoculated intranasally with RSV Memphis-37. Nine (67%) of the 12 older volunteers became infected, developing mild-to-moderate upper respiratory tract symptoms that resolved without serious adverse events or sequelae. Viral load peaked on day 6 post-inoculation and symptoms busy pictures to talk about

Publication : USDA ARS - Agricultural Research Service

WebMar 18, 2014 · RSV Memphis strain 37 (RSV M37) was frozen at varying sucrose concentrations (0%, 3%, 5%, 8%, 10%, 15%, and 20%) to assess infectivity after cryo … WebApr 1, 2014 · The Memphis 37 clinical strain of human RSV has been used to produce mild to moderate upper respiratory disease in healthy adult volunteers. We hypothesized that … WebJan 1, 2012 · Memphis 37 is an RSV-A strain isolated from a pediatric case and used in studies in human adult subjects. The overarching goal of the studies undertaken was to develop a model of enhanced RSV that could be utilized for investigating the pathogenesis of enhanced disease as well as therapeutic regimens. The central hypothesis for these … busy place for shipping crossword